Conclusion
Conclusion ( 5 Questions)
Which of the following routes of drug administration bypasses first-pass metabolism?
Oral administration does not bypass first-pass metabolism because drugs must first pass through the liver before entering the systemic circulation.
Intravenous administration bypasses first-pass metabolism because drugs are injected directly into the bloodstream, avoiding metabolism in the liver before entering the systemic circulation.
Sublingual administration partially bypasses first-pass metabolism because some of the drugs is absorbed directly into the bloodstream through the mucous membranes under the tongue, but some may still be swallowed and subject to first-pass metabolism.
Rectal administration partially bypasses first-pass metabolism because some of the drugs is absorbed directly into the bloodstream through the rectal mucosa, but some may still be subject to first-pass metabolism.
Intravenous administration bypasses first-pass metabolism because drugs are injected directly into the bloodstream, avoiding metabolism in the liver before entering the systemic circulation.
a. Oral administration does not bypass first-pass metabolism because drugs must first pass through the liver before entering the systemic circulation.
c. Sublingual administration partially bypasses first-pass metabolism because some of the drugs is absorbed directly into the bloodstream through the mucous membranes under the tongue, but some may still be swallowed and subject to first-pass metabolism.
d. Rectal administration partially bypasses first-pass metabolism because some of the drugs is absorbed directly into the bloodstream through the rectal mucosa, but some may still be subject to first-pass metabolism.