Heparins
Heparins ( 5 Questions)
A nurse is administering protamine sulfate to a client who has received an overdose of heparin. What are some important nursing considerations for this medication?
Protamine sulfate should be given slowly intravenously within 30 minutes of heparin administration. This is because protamine sulfate is a strong base that neutralizes the anticoagulant effect of heparin, which is a strong acid. Protamine sulfate should be given within 30 minutes of heparin administration to prevent excessive bleeding or hemorrhage. Protamine sulfate should be given slowly intravenously to avoid adverse effects such as hypotension, bradycardia, pulmonary edema, and anaphylaxis.
Choice B is wrong because protamine sulfate should not be given rapidly or intramuscularly. Rapid administration can cause severe hypotension and shock, and intramuscular administration can cause local irritation and hematoma formation.
Choice C is wrong because protamine sulfate should not be given more than 60 minutes after heparin administration. The half-life of heparin is 60 to 90 minutes, and the anticoagulant effect of heparin will usually wear off within a few hours after discontinuation. Giving protamine sulfate after 60 minutes may cause excess anticoagulation or “heparin rebound” due to the longer half-life of protamine sulfate. Choice D is wrong for the same reasons as choice B. Protamine sulfate should not be given rapidly or intramuscularly.
Choice D is wrong for the same reasons as choice B. Protamine sulfate should not be given rapidly or intramuscularly.
Protamine sulfate should be given slowly intravenously within 30 minutes of heparin administration. This is because protamine sulfate is a strong base that neutralizes the anticoagulant effect of heparin, which is a strong acid. Protamine sulfate should be given within 30 minutes of heparin administration to prevent excessive bleeding or hemorrhage. Protamine sulfate should be given slowly intravenously to avoid adverse effects such as hypotension, bradycardia, pulmonary edema, and anaphylaxis.
Choice B is wrong because protamine sulfate should not be given rapidly or intramuscularly. Rapid administration can cause severe hypotension and shock, and intramuscular administration can cause local irritation and hematoma formation.
Choice C is wrong because protamine sulfate should not be given more than 60 minutes after heparin administration. The half-life of heparin is 60 to 90 minutes, and the anticoagulant effect of heparin will usually wear off within a few hours after discontinuation. Giving protamine sulfate after 60 minutes may cause excess anticoagulation or “heparin rebound” due to the longer half-life of protamine sulfate.
Choice D is wrong for the same reasons as choice B. Protamine sulfate should not be given rapidly or intramuscularly.