Immunodefeciency disorders
Immunodefeciency disorders ( 50 Questions)
X-linked agammaglobulinemia is a primary immunodeficiency disorder that primarily affects B cell function, leading to a deficiency of immunoglobulins (antibodies).
The correct answer is b. DiGeorge syndrome. This disorder is caused by a deletion in chromosome 22, resulting in the underdevelopment of the thymus and parathyroid glands. It leads to impaired T cell function and is associated with developmental delays, chronic infections, and autoimmune problems.
Wiskott-Aldrich syndrome is an X-linked recessive disorder characterized by a triad of symptoms: eczema, thrombocytopenia (low platelet count), and immunodeficiency.
Severe combined immunodeficiency (SCID) is a group of rare disorders characterized by a severe deficiency of T cells, B cells, and natural killer (NK) cells.
Explanation: The correct answer is b. DiGeorge syndrome. This disorder is caused by a deletion in chromosome 22, resulting in the underdevelopment of the thymus and parathyroid glands. It leads to impaired T cell function and is associated with developmental delays, chronic infections, and autoimmune problems.
Incorrect choices:
a. X-linked agammaglobulinemia is a primary immunodeficiency disorder that primarily affects B cell function, leading to a deficiency of immunoglobulins (antibodies).
c. Wiskott-Aldrich syndrome is an X-linked recessive disorder characterized by a triad of symptoms: eczema, thrombocytopenia (low platelet count), and immunodeficiency.
d. Severe combined immunodeficiency (SCID) is a group of rare disorders characterized by a severe deficiency of T cells, B cells, and natural killer (NK) cells.