Choice A rationale:

To increase the number of abnormal white blood cells.

Rationale: The primary goal of chemotherapy in leukemia management is to decrease the number of abnormal white blood cells in the body.

Chemotherapy agents are used to target and destroy rapidly dividing cancer cells, including the abnormal white blood cells produced in leukemia.

Increasing the number of abnormal white blood cells would be counterproductive to leukemia treatment.

Choice B rationale:

To reduce the risk of viral infections.

Rationale: While chemotherapy can weaken the immune system temporarily, its primary goal is not to reduce the risk of viral infections.

Chemotherapy is administered to target cancer cells and reduce their numbers.

However, it does come with the side effect of suppressing the immune system, making patients more susceptible to infections of various types, including viral infections.

Choice C rationale:

To promote the proliferation of normal blood cells.

Rationale: Chemotherapy's primary goal in leukemia management is not to promote the proliferation of normal blood cells.

While it may indirectly help in restoring normal blood cell production by reducing the competition from abnormal white blood cells, its primary focus is on targeting and reducing the population of cancerous white blood cells.

Choice D rationale:

To decrease the number of abnormal white blood cells in the body.

Rationale: This is the correct answer.

Chemotherapy in leukemia management aims to reduce the number of abnormal white blood cells, thereby controlling the progression of the disease and alleviating symptoms associated with leukemia.