More questions on this topic

More questions on this topic ( 31 Questions)

Which antibiotics are classified as concentration-dependent antimicrobials?



Correct Answer: E

Gentamicin is an example of a concentration-dependent antimicrobial, which means that it achieves increasing bacterial kill with increasing levels of drug. The peak concentration and the area under the concentration curve (AUC) determine the efficacy of these antibiotics. Other examples of concentration-dependent antimicrobials include fluoroquinolones, daptomycin, aminoglycosides, and amphotericin

Choice A is wrong because ciprofloxacin is a fluoroquinolone, which is also a concentration-dependent antimicrobial.

Choice B is wrong because imipenem is a carbapenem, which is a type of beta-lactam antibiotic. Beta-lactams are time-dependent antimicrobials, which means that their bactericidal activity depends on the duration of the effective concentration.

Choice C is wrong because penicillin V is another type of beta-lactam antibiotic, which is also a time-dependent antimicrobial.

Choice D is wrong because metronidazole is a bactericidal agent that has both time- and concentration-dependent properties. However, it is not classified as a concentration-dependent antimicrobial according to the AMEG categorization of antibiotics in the European Union.




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