Nephrogenic Diabetes Insipidus

Nephrogenic Diabetes Insipidus ( 35 Questions)

A nurse is discussing the genetic forms of Nephrogenic Diabetes Insipidus. Which of the following is an X-linked recessive form of the condition?



Correct Answer: D

A) Incorrect. Autosomal dominant Nephrogenic Diabetes Insipidus is inherited in an autosomal dominant manner, not as an X-linked recessive trait.

B) Incorrect. Autosomal recessive Nephrogenic Diabetes Insipidus is inherited in an autosomal recessive manner, not as an X-linked recessive trait.

C) Incorrect. X-linked dominant inheritance is not associated with Nephrogenic Diabetes Insipidus. This condition can be caused by mutations in the AVPR2 gene (X-linked recessive) or the AQP2 gene (autosomal recessive).

D) Correct. X-linked recessive Nephrogenic Diabetes Insipidus is caused by mutations in the AVPR2 gene located on the X chromosome. It primarily affects males who inherit the mutated gene from their carrier mothers.




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