Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Nonsteroidal Anti-inflammatory Drugs (NSAIDs) ( 5 Questions)
A client is prescribed selective COX-2 inhibitors for pain relief.
Which of the following statements by the client indicates an understanding of the teaching?
These medications do not block both COX-1 and COX-2 enzymes, but only COX-2 enzymes.
It is an incomplete statement. These medications do block only COX-2 enzymes, but this does not explain how they differ from nonselective COX inhibitors.
These medications have less gastrointestinal and bleeding side effects than nonselective COX inhibitors. This is because selective COX-2 inhibitors block only COX-2 enzymes, which are mainly involved in inflammation, and do not affect COX-1 enzymes, which help protect the stomach and intestinal lining and control blood clotting.
It is a potential adverse effect of these medications, not a benefit. These medications may increase the risk of cardiovascular events such as myocardial infarction and stroke by reducing the production of prostacyclin, which inhibits platelet aggregation and vasodilation.
These medications have less gastrointestinal and bleeding side effects than nonselective COX inhibitors. This is because selective COX-2 inhibitors block only COX-2 enzymes, which are mainly involved in inflammation, and do not affect COX-1 enzymes, which help protect the stomach and intestinal lining and control blood clotting.
Choice A is wrong because these medications do not block both COX-1 and COX-2 enzymes, but only COX-2 enzymes.
Choice B is wrong because it is an incomplete statement. These medications do block only COX-2 enzymes, but this does not explain how they differ from nonselective COX inhibitors.
Choice D is wrong because it is a potential adverse effect of these medications, not a benefit. These medications may increase the risk of cardiovascular events such as myocardial infarction and stroke by reducing the production of prostacyclin, which inhibits platelet aggregation and vasodilation.