Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Nonsteroidal Anti-inflammatory Drugs (NSAIDs) ( 5 Questions)
A nurse is caring for a patient who is prescribed nonselective COX inhibitors for pain relief.
Which of the following statements by the nurse indicates an understanding of the medication?
Nonselective COX inhibitors block both COX-1 and COX-2 enzymes. Blocking COX-1 can cause gastrointestinal and bleeding side effects.
Nonselective COX inhibitors have more gastrointestinal and bleeding side effects than selective COX-2 inhibitors. This is because selective COX-2 inhibitors spare the COX-1 enzyme that protects the stomach and intestinal lining.
Nonselective COX inhibitors are indicated for mild to moderate pain caused by inflammation, injury, surgery, dysmenorrhea, headache, fever, and cancer. This statement reflects an understanding of the medication’s mechanism of action and indications.
Nonselective COX inhibitors are not available in intravenous or intra-articular forms. Only selective COX-2 inhibitors such as celecoxib have these formulations.
Nonselective COX inhibitors are indicated for mild to moderate pain caused by inflammation, injury, surgery, dysmenorrhea, headache, fever, and cancer. This statement reflects an understanding of the medication’s mechanism of action and indications.
Choice A is wrong because nonselective COX inhibitors block both COX-1 and COX-2 enzymes. Blocking COX-1 can cause gastrointestinal and bleeding side effects.
Choice B is wrong because nonselective COX inhibitors have more gastrointestinal and bleeding side effects than selective COX-2 inhibitors. This is because selective COX-2 inhibitors spare the COX-1 enzyme that protects the stomach and intestinal lining.
Choice D is wrong because nonselective COX inhibitors are not available in intravenous or intra-articular forms. Only selective COX-2 inhibitors such as celecoxib have these formulations.