Nursing Assessments, Interventions, and Education for Patients Receiving Analgesics
Nursing Assessments, Interventions, and Education for Patients Receiving Analgesics ( 5 Questions)
A nurse is reviewing the medication administration record of a client who is receiving tramadol for moderate pain.
The nurse should identify that which of the following medications can interact with tramadol and increase the risk of serotonin syndrome?
Omeprazole is not known to affect serotonin levels or interact with tramadol.
Metformin is not known to affect serotonin levels or interact with tramadol.
Fluoxetine can interact with tramadol and increase the risk of serotonin syndrome. Serotonin syndrome is a serious drug reaction that occurs when there is too much serotonin in the body. It can cause symptoms such as agitation, confusion, muscle rigidity, seizures, and coma.
Lisinopril is not known to affect serotonin levels or interact with tramadol.
Fluoxetine can interact with tramadol and increase the risk of serotonin syndrome. Serotonin syndrome is a serious drug reaction that occurs when there is too much serotonin in the body. It can cause symptoms such as agitation, confusion, muscle rigidity, seizures, and coma.
Choice A is wrong because omeprazole is not known to affect serotonin levels or interact with tramadol.
Choice B is wrong because metformin is not known to affect serotonin levels or interact with tramadol.
Choice D is wrong because lisinopril is not known to affect serotonin levels or interact with tramadol.
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases the amount of serotonin available in the brain.
Tramadol is an opioid pain medication that also has some serotonin and norepinephrine reuptake inhibitory effects. When these two drugs are taken together, they can cause a buildup of excess serotonin that can lead to serotonin syndrome.
This is a rare but potentially life-threatening condition that requires immediate medical attention.
Normal ranges of serotonin in the blood are between 101 and 283 nanograms per milliliter (ng/mL).
Serotonin syndrome can occur when serotonin levels exceed 500 ng/mL.