Nursing implications and patient education
Nursing implications and patient education ( 5 Questions)
A nurse is administering gentamicin, an aminoglycoside antibiotic, to a patient who has a gram-negative infection.
The nurse monitors the patient’s serum creatinine level as an indicator of what?
Choice A is wrong because hepatotoxicity is the damage of the liver, not the kidney.
Gentamicin is not known to cause hepatotoxicity.
Gentamicin is an aminoglycoside antibiotic that can cause nephrotoxicity, which is the damage of the kidney. Gentamicin induces nephrotoxicity by inhibiting protein synthesis in renal cells that specifically causes necrosis of cells in the renal proximal tubule, resulting in acute tubular necrosis, followed by acute renal failure. The nurse monitors the patient’s serum creatinine level as an indicator of nephrotoxicity because serum creatinine reflects the glomerular filtration rate (GFR) and kidney function.
Choice C is wrong because neurotoxicity is the damage of the nervous system, not the kidney.
Gentamicin can cause neurotoxicity by affecting the neuromuscular junction and causing muscle weakness or paralysis, but this is not related to serum creatinine level.
Choice D is wrong because ototoxicity is the damage of the ear, not the kidney.
Gentamicin can cause ototoxicity by damaging the hair cells in the inner ear and causing hearing loss or balance problems, but this is not related to serum creatinine level.
Gentamicin is an aminoglycoside antibiotic that can cause nephrotoxicity, which is the damage of the kidney. Gentamicin induces nephrotoxicity by inhibiting protein synthesis in renal cells that specifically causes necrosis of cells in the renal proximal tubule, resulting in acute tubular necrosis, followed by acute renal failure. The nurse monitors the patient’s serum creatinine level as an indicator of nephrotoxicity because serum creatinine reflects the glomerular filtration rate (GFR) and kidney function.
Choice A is wrong because hepatotoxicity is the damage of the liver, not the kidney.
Gentamicin is not known to cause hepatotoxicity.
Choice C is wrong because neurotoxicity is the damage of the nervous system, not the kidney.
Gentamicin can cause neurotoxicity by affecting the neuromuscular junction and causing muscle weakness or paralysis, but this is not related to serum creatinine level.
Choice D is wrong because ototoxicity is the damage of the ear, not the kidney.
Gentamicin can cause ototoxicity by damaging the hair cells in the inner ear and causing hearing loss or balance problems, but this is not related to serum creatinine level.
Normal ranges for serum creatinine are 0.6 to 1.2 mg/dL for men and 0.5 to 1.1 mg/dL for women.