Signs and symptoms
Signs and symptoms ( 9 Questions)
A nurse is reviewing the medication history of a client who is prescribed lithium carbonate (Lithobid) for bipolar disorder. Which of the following medications should alert the nurse to a potential drug interaction?
Rationale: Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the blood levels of lithium by reducing its renal excretion. This can result in lithium toxicity, which can cause nausea, vomiting, tremors, confusion, and seizures.
Levothyroxine and other thyroid hormones do not interact with lithium.
Omeprazole and other proton pump inhibitors (PPIs) do not interact with lithium.
Metformin and other antidiabetic drugs do not interact with lithium.
Correct answer: a) Ibuprofen (Advil)
Rationale: Ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the blood levels of lithium by reducing its renal excretion. This can result in lithium toxicity, which can cause nausea, vomiting, tremors, confusion, and seizures.
Incorrect choices:
b) Levothyroxine (Synthroid): Levothyroxine and other thyroid hormones do not interact with lithium.
c) Omeprazole (Prilosec): Omeprazole and other proton pump inhibitors (PPIs) do not interact with lithium.
d) Metformin (Glucophage): Metformin and other antidiabetic drugs do not interact with lithium.