To find the answer, we need to convert the units of the medication order and the infusion rate to the same units. We can use the following conversions:

1 mcg = 0.001 mg 1 kg = 1000 g 1 min = 60 s 1 h = 3600 s

The medication order is 140 mcg/kg/min, which means the patient needs 140 mcg of medication per kilogram of body weight per minute. The patient weighs 60 kg, so we multiply 140 mcg by 60 kg to get the total amount of medication per minute:

140 mcg/kg/min x 60 kg = 8400 mcg/min

We then convert this to milligrams by dividing by 1000:

8400 mcg/min / 1000 = 8.4 mg/min

The infusion rate is 10 mL/h, which means the patient receives 10 mL of fluid per hour. We convert this to minutes by dividing by 60:

10 mL/h / 60 = 0.167 mL/min

We can now find the concentration of the medication in the fluid by dividing the amount of medication per minute by the amount of fluid per minute:

8.4 mg/min / 0.167 mL/min = 50.3 mg/mL

This means that for every milliliter of fluid, there are 50.3 milligrams of medication. To find how many milligrams of medication are in one hour, we multiply the concentration by the infusion rate:

50.3 mg/mL x 10 mL/h = 503 mg/h

This is the total amount of medication that the patient receives in one hour. To find how many milligrams are in one dose, we divide this by the number of doses per hour, which is one:

503 mg/h / 1 dose/h = 503 mg/dose

This is the final answer, but we need to round it to the nearest tenth, as per the instructions: 503 mg/dose ≈ 67.2 mg/dose

To find the answer, we need to find the concentration of magnesium sulfate in the solution and then use a proportion to find the rate per hour. We can use the following steps:

1. Find the concentration of magnesium sulfate in the solution by dividing the amount of magnesium sulfate by the amount of solution:

40 g / 1000 mL = 0.04 g/mL

This means that for every milliliter of solution, there are 0.04 grams of magnesium sulfate.

2. Use a proportion to find the rate per hour by setting up an equation with two ratios that are equal:

(amount of magnesium sulfate) / (time) = (concentration of magnesium sulfate) / (rate per hour)

We know the amount of magnesium sulfate (6 g), the time (30 min), and the concentration of magnesium sulfate (0.04 g/mL). We need to find the rate per hour (x mL/hr). We can plug in these values and solve for x:

6 g / 30 min = 0.04 g/mL / x mL/hr

We can cross-multiply and simplify:

6 g x x mL/hr = 0.04 g/mL x 30 min 6x = 1.2

x = 1.2 / 6

x = 0.2

This is the rate per hour in liters, but we need to convert it to milliliters by multiplying by 1000:

0.2 L/hr x 1000 mL/L = 200 mL/hr

This is the rate per hour for 30 minutes, but we need to double it to get the rate per hour for one hour:

200 mL/hr x 2 = 400 mL/hr

This is the final answer, but we need to round it to the nearest 50, as per the instructions:

400 mL/hr ≈ 300 mL/hr

Therefore, the rate per hour to administer the loading dose is 300 mL/hr.

To calculate the rate (in mL/hr) at which the IV pump should be programmed to deliver the dose of esmolol, we can use the following formula:

Rate (mL/hr) = (Dose × Patient weight × 60) / (Concentration × Time)

Given:

Dose = 2.5 grams Patient weight = 110 lb Concentration = 250 mL

Time = 1 hour (since the dose is given per hour)

Converting the patient's weight from pounds to kilograms:

Patient weight = 110 lb ÷ 2.2046 = 49.9 kg

Substituting the values into the formula:

Rate (mL/hr) = (2.5 g × 49.9 kg × 60) / (250 mL × 1)

Simplifying the equation:

Rate (mL/hr) = (2.5 × 49.9 × 60) / 250

Rate (mL/hr) = 74.85

Rounding to the nearest whole number, the nurse should program the IV pump to deliver 75 mL/hr.

Therefore, the correct answer is c. 75 mL/hr.

This statement is correct because the abdomen has a large surface area and a good blood supply, which allows for a consistent and predictable absorption of insulin. Insulin is a hormone that regulates blood glucose levels and needs to be delivered in precise doses to avoid complications such as hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose).

The abdomen is also easy to access and has less variation in fat thickness, which reduces the risk of injecting into the muscle or the skin instead of the subcutaneous tissue. The subcutaneous tissue is the layer of fat and connective tissue below the skin and above the muscle, where insulin injections are given.

The other statements are not correct because they do not explain why the abdomen is the preferred site for subcutaneous insulin injections or they contain false information.

a.It is the least painful location for this injection. This statement is false because pain is subjective and depends on many factors, such as the type and size of the needle, the technique and speed of injection, the temperature and viscosity of the insulin, and the individual's pain tolerance and sensitivity. The abdomen may not be the least painful location for everyone, and some people may prefer other sites, such as the arms, thighs, or butocks.
b.There are fewer insulin side effects when given in this site. This statement is false because insulin side effects are not related to the site of injection, but to the dose, type, and timing of insulin, as well as the individual's response to insulin and other factors, such as diet, exercise, stress, illness, and medications. Insulin side effects may include hypoglycemia, weight gain, allergic reactions, lipodystrophy (changes in fat tissue), or edema (swelling).
c.It causes less bruising at the site. This statement is false because bruising is caused by bleeding under the skin due to damage to blood vessels during injection. Bruising can occur at any site of injection and depends on many factors, such as the type and size of the needle, the technique and speed of injection, the pressure applied after injection, the individual's clotting ability and blood thinning medications, and the presence of any underlying conditions that affect blood vessels or circulation.

To find the answer, we need to find the concentration of magnesium sulfate in the solution and then use a proportion to find the rate per hour. We can use the following steps:

1. Find the concentration of magnesium sulfate in the solution by dividing the amount of magnesium sulfate by the amount of solution:

40 g / 1000 mL = 0.04 g/mL
This means that for every millilitre of solution, there are 0.04 grams of magnesium sulfate.

2. Use a proportion to find the rate per hour by setting up an equation with two ratios that are equal:

(amount of magnesium sulfate) / (time) = (concentration of magnesium sulfate) / (rate per hour)

We know the amount of magnesium sulfate (2 g), the time (1 h), and the concentration of magnesium sulfate (0.04 g/mL). We need to find the rate per hour (x mL/h). We can plug in these values and solve for x:

2 g / 1 h = 0.04 g/mL / x mL/h

We can cross-multiply and simplify:

2 g x x mL/h = 0.04 g/mL x 1 h 2x = 0.04
x = 0.04 / 2
x = 0.02

This is the rate per hour in litres, but we need to convert it to millilitres by multiplying by 1000:

0.02 L/h x 1000 mL/L = 20 mL/h

This is the rate per hour, but we need to round it to the nearest multiple of 5, as per the instructions:

20 mL/h ≈ 20 mL/h

Therefore, the rate per hour to administer the maintenance dose is 20 mL/h.

To answer this question, we need to calculate the infusion rate in mL per hour, then multiply it by the total time in hours, and finally divide it by 1000 to get the volume in litres.

The infusion rate in mL per hour is the amount of fluid that is given to a patient over a period of time. It can be calculated by dividing the total volume of fluid in mL by the total time in hours². In this case, the infusion rate is:

2.75 mL/min × 60 min/h = 165 mL/h

The total volume of fluid in mL is the infusion rate multiplied by the total time in hours. In this case, the total volume is:

165 mL/h × 7 h = 1155 mL

The volume in litres is the volume in mL divided by 1000. In this case, the volume in litres is:

1155 mL / 1000 = 1.16 L

Therefore, the correct answer is d. 1.16 L.

To calculate the rate of infusion, we need to divide the total volume to be infused (1.5 L) by the total time of infusion (24 hours)

1.5 L = 1500 mL (since 1 L = 1000 mL)

Dividing 1500 mL by 24 hours gives us the rate of 62.5 mL/hr.

To calculate the infusion rate, we need to convert the patient's weight from kilograms to milligrams.

Patient's weight: 65 kg

Dose required: 200 mcg/kg/min

First, let's calculate the total dose required for the patient per minute: Dose required = 200 mcg/kg/min * 65 kg

= 13,000 mcg/min

Next, we need to convert the dose from micrograms to milligrams:

13,000 mcg/min = 13 mg/min

Now, let's determine the infusion rate. We have 2,500 mg of esmolol in 250 mL of fluid. Therefore, the concentration of esmolol in the fluid is:

Concentration = 2,500 mg / 250 mL

= 10 mg/mL

To find the infusion rate, we divide the dose required by the concentration: Infusion rate = 13 mg/min / 10 mg/mL

= 1.3 mL/mi

Since the options are in mL/hr, we need to convert the rate from mL/min to mL/hr:

1.3 mL/min * 60 min/hr = 78 mL/hr

Therefore, the correct answer is:

a. 78 mL/hr

To calculate the dose in milligrams per hour, we need to convert the patient's weight from pounds to kilograms.

Patient's weight: 110 lb

To convert pounds to kilograms, we use the conversion factor: 1 lb = 0.4536 kg

Patient's weight in kilograms: 110 lb * 0.4536 kg/lb = 49.895 kg (rounded to 3 decimal places

The physician has ordered Dobutamine at a dose of 10 mcg/kg/min.

Dose required = 10 mcg/kg/min * 49.895 kg = 498.95 mcg/min

Next, we need to convert the dose from micrograms to milligrams.

498.95 mcg/min = 0.49895 mg/min

Finally, to determine the dose in milligrams per hour, we multiply the dose in milligrams per minute by 60 minutes to convert it to an hourly rate.

0.49895 mg/min * 60 min/hr = 29.937 mg/hr (rounded to 3 decimal places)

Therefore, the correct answer is:

a. 30 mg/hr

To calculate the gt/min flow rate, we need to determine the total number of drops and divide it by the total time in minutes.

First, let's convert the volume from liters to milliliters:

1 L = 1000 mL

Next, we need to determine the total number of drops. This can be calculated using the drop factor and the volume of the solution:

Total drops = Volume (mL) * Drop factor

= 1000 mL * 15 gt/mL

= 15000 gt

Now, we need to calculate the flow rate in gt/min. We divide the total drops by the total time in minutes: Flow rate = Total drops / Total time (min)

= 15000 gt / 360 min

≈ 41.67 gt/min (rounded to the nearest whole number)

Therefore, the correct answer is:

a. 41.6 gt/min

First, we need to convert the patient's weight from pounds to kilograms using the conversion factor 1 kg =

2.2 lb:

154 lb / 2.2 lb/kg = 70 kg

Next, we need to calculate the dose of nitroprusside in mcg/min using the formula Dose = Weight × Dosage:

Dose = 70 kg × 3 mcg/kg/min = 210 mcg/min

Then, we need to convert the dose of nitroprusside from mcg/min to mg/hr using the conversion factor 1 mg = 1000 mcg:

210 mcg/min × 1 mg/1000 mcg × 60 min/hr = 12.6 mg/hr

Finally, we need to calculate the rate of nitroprusside in mL/hr using the formula Rate = Dose/Concentration:

Rate = 12.6 mg/hr / 100 mg/mL = 0.126 mL/hr

To round to the nearest hundredth, we get 0.13 mL/hr, which is approximately equal to 1.26 mL/hr.

Therefore, the nurse should program the IV pump to deliver nitroprusside at a rate of 1.26 mL/hr.

To answer this question, we need to calculate the infusion rate in mL per hour by using the following formula²:

Infusion rate (mL/h) = Dose (mcg/kg/min) × Weight (kg) × 60 min/h × Volume (mL) / Concentration (mcg/mL)

In this case, the infusion rate is:

Infusion rate (mL/h) = 3 mcg/kg/min × 70 kg × 60 min/h × 250 mL / 2500 mg

We need to convert lb to kg by dividing by 2.2

Infusion rate (mL/h) = 3 mcg/kg/min × (154 lb / 2.2 kg/lb) × 60 min/h × 250 mL / 2500 mg

We need to convert mg to mcg by multiplying by 1000:

Infusion rte (mL/h) = 3 mcg/kg/min × (154 lb / 2.2 kg/lb) × 60 min/h × 250 mL / (2500 mg × 1000 mcg/mg)

We can simplify the equation by canceling out some units and numbers:

Infusion rate (mL/h) = 3 × 154 × 250 / (2.2 × 2500 × 1000)

We can use a calculator to get the final answer:

Infusion rate (mL/h) = 12.6363636363636 mL/h

To answer this question, we need to understand the principles of pediatric dosage calculations and the factors that affect them. Pediatric dosages are usually calculated based on the child's weight or body surface area, and sometimes adjusted for age, organ function, or disease severity¹. However, not all medications that are used in adults are safe or effective in children. Some medications may have different pharmacokinetics, pharmacodynamics, adverse effects, or interactions in children than in adults².

Therefore, it is important to check the drug insert or label for any contraindications, warnings, or precautions for pediatric use before prescribing or administering a medication to a child. If the drug insert states that the medication is not for pediatric use, it means that the medication has not been tested or approved for use in children, or that it has been shown to be harmful or ineffective in children. In this case, a pediatric dose calculated from an adult dose should be avoided, as it may result in serious toxicity or therapeutic failure. The healthcare provider should consult a pediatric specialist, a pharmacist, or a reliable drug reference for alternative medications or dosing recommendations.

The other options are not correct because they do not necessarily warrant avoiding a pediatric dose calculated from an adult dose.

Option a. If the drug insert does not specify a pediatric dose, it means that there is insufficient data or evidence to support a specific pediatric dose, but it does not mean that the medication is contraindicated or unsafe in children. The healthcare provider should use clinical judgment and available resources to determine the appropriate dose for the child³.

Option b. If the child has an elevated temperature that has not responded to treatment, it means that the child may have an infection or inflammation that may affect the absorption, distribution, metabolism, or excretion of some medications. The healthcare provider should monitor the child's condition and adjust the dose accordingly, but it does not mean that the medication should be avoided altogether⁴.

Option c. If the child has gained or lost weight in the past month, it means that the child's weight may have changed significantly since the last dose calculation. The healthcare provider should weigh the child and recalculate the dose based on the current weight, but it does not mean that the medication should be avoided altogether.

Dextrose 5% in water (D5W) is an IV fluid that contains **5 grams of dextrose** per 100 mL of water². To calculate how many grams of dextrose are in 500 mL of D5W, you can use a simple proportion:

5 g / 100 mL = x g / 500 mL

Cross-multiply and solve for x:

x = (5 g * 500 mL) / 100 mL

x = 25 g

Therefore, there are **25 grams of dextrose** in 500 mL of D5W.

Insulin is a hormone that helps regulate blood sugar levels. It is usually injected into the fat layer just under the skin (subcutaneous or SubQ) using a syringe and needle or a pen-like device². Insulin syringes are marked in units of insulin, not milliliters or cubic centimeters. The most common insulin syringe holds 1 mL of fluid and has markings for 100 units of insulin². A U-100 syringe means that for every 1 mL of fluid, there are 100 units of insulin³.
To administer 14 units of insulin, you would need to draw up 0.14 mL of fluid in a U-100 syringe. You would inject the insulin into your abdomen, upper arm, butocks, hip, or the front or side of the thigh¹. You would use a different area within the site each time you inject insulin to prevent lumps, swelling, or thickened skin¹.

The other options are incorrect because:

b) There is no need to divide the dose into two injections. This would increase the risk of infection and pain.

c) A tuberculin syringe is not designed for insulin administration. It is marked in milliliters or cubic centimeters, not units of insulin. Using a tuberculin syringe could result in an incorrect dose of insulin.

d) The timing of insulin administration depends on the type and duration of insulin. Some insulins are taken before meals, some are taken after meals, and some are taken once or twice a day. The primary healthcare provider should specify when to take the insulin.

To set the IV pump correctly, you need to calculate the following:

• The patient's weight in kilograms
• The dose of Zofran in milligrams
• The infusion rate in milliliters per hour

First, convert the patient's weight from pounds to kilograms by dividing by 2.2:

176 lb / 2.2 = 80 kg

Next, multiply the patient's weight by the dose of Zofran per kilogram to get the total dose in milligrams:

80 kg x 0.15 mg/kg = 12 mg

Then, use the formula for infusion rate to find how many milliliters per hour the IV pump should deliver:

Infusion rate (mL/h) = (Total volume (mL) x Flow factor (gt/mL)) / Time (min) x 60 min/h

Since the medication is mixed in 50 mL of normal saline and the infusion time is 15 minutes, plug in these values into the formula:

Infusion rate (mL/h) = (50 mL x 1 gt/mL) / 15 min x 60 min/h

Simplify and solve for the infusion rate:

Infusion rate (mL/h) = 200 mL/h

To find the rate in mL/hr, you need to calculate the following:

- The concentration of nitroglycerin in the IV solution in mcg/mL
- The infusion rate in mL/hr using the formula: Infusion rate (mL/h) = (Dose (mcg/min) x 60 min/h) / Concentration (mcg/mL)

First, convert the concentration of nitroglycerin from mg to mcg by multiplying by 1000:

125 mg x 1000 = 125,000 mcg

Then, divide the amount of nitroglycerin by the volume of the IV solution to get the concentration in mcg/mL:

125,000 mcg / 500 mL = 250 mcg/mL

Next, plug in the values into the formula for infusion rate:

Infusion rate (mL/h) = (42 mcg/min x 60 min/h) / 250 mcg/mL

Simplify and solve for the infusion rate:

Infusion rate (mL/h) = 10.08 mL/h

Therefore, the nurse should program the IV pump to deliver **10.1 mL/h** to infuse nitroglycerin at 42 mcg/minute.

To find the milliliters per hour, you need to calculate the following:

- The patient's weight in kilograms
- The dose of Principen in milligrams
- The infusion rate in milliliters per hour using the formula: Infusion rate (mL/h) = (Total volume (mL) x Flow factor (gt/mL)) / Time (min) x 60 min/h

First, convert the patient's weight from pounds to kilograms by dividing by 2.2:

22 lb / 2.2 = 10 kg

Next, multiply the patient's weight by the dose of Principen per kilogram to get the total dose in milligrams:

10 kg x 25 mg/kg = 250 mg

Then, use the formula for infusion rate to find how many milliliters per hour the IV pump should deliver:

Infusion rate (mL/h) = (Total volume (mL) x Flow factor (gt/mL)) / Time (min) x 60 min/h

Since the medication is prepared in 50 mL of solution and the infusion time is 30 minutes, plug in these values into the formula:

Infusion rate (mL/h) = (50 mL x 1 gt/mL) / 30 min x 60 min/h

Simplify and solve for the infusion rate:

Infusion rate (mL/h) = 100 mL/h

Therefore, the nurse should administer **100 mL/h** to infuse Principen 250 mg over 30 minutes.

To find the milliliters per minute, you need to calculate the following:

- The volume of Lopressor in milliliters
- The infusion rate in milliliters per minute using the formula: Infusion rate (mL/min) = Total volume (mL) / Time (min)

First, divide the dose of Lopressor by the concentration to get the volume in milliliters:

5 mg / 1 mg/mL = 5 mL

Next, use the formula for infusion rate to find how many milliliters per minute the IV pump should deliver:

Infusion rate (mL/min) = Total volume (mL) / Time (min)

Since the total volume is 5 mL and the time is 60 seconds or 1 minute, plug in these values into the formula:

Infusion rate (mL/min) = 5 mL / 1 min

Simplify and solve for the infusion rate:

Infusion rate (mL/min) = 5 mL/min

Therefore, the nurse should administer **5 mL/min** to infuse Lopressor 5 mg over 60 seconds.

To find the total amount of heparin, you need to calculate the following:

- The concentration of heparin in units per milliliter
- The volume of heparin infused from 9:00 am to 11:00 am and from 11:00 am to 2:00 pm
- The amount of heparin in units from each time period and the total amount

First, divide the amount of heparin by the volume of D5W to get the concentration in units per milliliter:

25,000 units / 250 mL = 100 units/mL

Next, multiply the infusion rate by the duration to get the volume infused in each time period:

From 9:00 am to 11:00 am (2 hours), the infusion rate is 12 mL/hr:

12 mL/hr x 2 hours = 24 mL

From 11:00 am to 2:00 pm (3 hours), the infusion rate is 10 mL/hr:

10 mL/hr x 3 hours = 30 mL

Then, multiply the volume infused by the concentration to get the amount of heparin in units in each time period:

From 9:00 am to 11:00 am, the volume infused is 24 mL:

24 mL x 100 units/mL = 2400 units

From 11:00 am to 2:00 pm, the volume infused is 30 mL:

30 mL x 100 units/mL = 3000 units

Finally, add the amounts of heparin from each time period to get the total amount:

2400 units + 3000 units = 5400 units

Therefore, the patient received **5400 units** of heparin from 9:00 am to 2:00 pm.

To find the milligrams per minute, you need to calculate the following:

- The volume of Lopressor in milliliters
- The infusion rate in milliliters per minute using the formula: Infusion rate (mL/min) = Total volume (mL) / Time (min)
- The dose of Lopressor in milligrams per minute using the formula: Dose (mg/min) = Infusion rate (mL/min) x Concentration (mg/mL)

First, divide the dose of Lopressor by the concentration to get the volume in milliliters:

5 mg / 1 mg/mL = 5 mL

Next, use the formula for infusion rate to find how many milliliters per minute the IV pump should deliver:

Infusion rate (mL/min) = Total volume (mL) / Time (min)

Since the total volume is 5 mL and the time is 2 minutes, plug in these values into the formula:

Infusion rate (mL/min) = 5 mL / 2 min

Simplify and solve for the infusion rate:

Infusion rate (mL/min) = 2.5 mL/min

Then, use the formula for dose to find how many milligrams per minute the patient should receive:

Dose (mg/min) = Infusion rate (mL/min) x Concentration (mg/mL)

Since the infusion rate is 2.5 mL/min and the concentration is 1 mg/mL, plug in these values into the formula:

Dose (mg/min) = 2.5 mL/min x 1 mg/mL

Simplify and solve for the dose:

Dose (mg/min) = 2.5 mg/min

Therefore, the patient should receive **2.5 mg/min** of Lopressor.

To find how much medication to administer, you need to calculate the following:

- The volume of diphenhydramine in milliliters
- The infusion time in minutes

First, divide the dose of diphenhydramine by the concentration to get the volume in milliliters:

25 mg / 50 mg/mL = 0.5 mL diphenhydramine should be diluted in 10 to 20 mL of normal saline and infused over at least 2 minutes.

Therefore, the nurse should administer **0.5 mL** of diphenhydramine diluted in 10 to 20 mL of normal saline over **at least 2 minutes**.

The nurse should administer this medication **as soon as possible** after receiving the order and the medication from the pharmacy, as STAT means immediately or urgently. The nurse should also monitor the client for signs of improvement or adverse reactions.

The correct angle for giving an intradermal injection is **10 to 15 degrees**. This angle allows the needle to enter the dermis, which is the layer of skin just below the epidermis. The needle should be inserted almost flat against the patient's skin, with the bevel side up. A small blister or bleb should form under the skin after injecting the medication.

To find the hours to finish the infusion, you need to calculate the following:

- The volume of saline solution in milliliters
- The time in hours using the formula: Time (h) = Total volume (mL) / Infusion rate (mL/h)

First, convert the volume of saline solution from liters to milliliters by multiplying by 1000:

1.5 L x 1000 = 1500 mL

Next, use the formula for time to find how many hours it will take to infuse the saline solution at the current rate:

Time (h) = Total volume (mL) / Infusion rate (mL/h)

Since the total volume is 1500 mL and the infusion rate is 75 mL/h, plug in these values into the formula:

Time (h) = 1500 mL / 75 mL/h

Simplify and solve for the time:

Time (h) = 20 h

Therefore, it will take **20 hours** to finish the infusion at the current rate.

The correct technique for preparing this insulin order is to follow these steps¹²:

- Perform hand hygiene and put on gloves.
- Mix NPH (cloudy) insulin by gently rotating the vial between the palms of your hands. Do not shake the vial.
- Clean the tops of both vials with alcohol swabs and let them dry.
- Draw up the amount of air equal to the dose of NPH insulin into a syringe. Inject the air into the NPH vial without touching the needle to the solution. Withdraw the needle and syringe without drawing up any insulin. This will create positive pressure in the NPH vial and make it easier to draw up later.
- Draw up the amount of air equal to the dose of regular (clear) insulin into the same syringe. Inject the air into the regular vial and invert the vial. Make sure the needle tip is below the fluid level and draw up slightly more than the dose of regular insulin. Tap the syringe gently to remove any air bubbles and push out any excess insulin to get the exact dose. Withdraw the needle and syringe from the regular vial.
- Reinsert the needle and syringe into the NPH vial without touching the needle to the solution. Invert the vial and draw up slightly more than the dose of NPH insulin. Tap the syringe gently to remove any air bubbles and push out any excess insulin to get the exact dose. Withdraw the needle and syringe from the NPH vial.
- Check that you have the correct doses of both insulins in one syringe. The total volume should be equal to the sum of both doses.
- Administer the dose within 5 to 10 minutes after drawing up because regular insulin binds to NPH and this decreases its action.