Antibiotics and Antimicrobial Agents > Pharmacology
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Showing 5 questions, Sign in for moreA nurse is reviewing the medication history of a client who has a urinary tract infection caused by Escherichia coli.
Which of the following antimicrobial agents should the nurse expect the provider to prescribe for this client?
Explanation
Amoxicillin-clavulanate is an antibiotic that belongs to the penicillin group and is effective against Escherichia coli, the most common cause of urinary tract infections (UTIs).It works by inhibiting the bacterial cell wall synthesis and preventing the bacteria from producing an enzyme that makes them resistant to penicillin.
Choice B is wrong becauseVancomycin is wrong because it is an antibiotic that is used to treat serious infections caused by gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA).It is not effective against gram-negative bacteria, such as Escherichia coli.
Choice C is wrong becausePenicillin G is wrong because it is an antibiotic that is effective against some gram-positive bacteria, such as Streptococcus and Neisseria.However, many strains of Escherichia coli are resistant to penicillin G and can produce an enzyme called beta-lactamase that breaks down the antibiotic.
Choice D is wrong becauseAcyclovir is wrong because it is an antiviral drug that is used to treat infections caused by herpes simplex virus (HSV) and varicella-zoster virus (VZV).It has no activity against bacteria, such as Escherichia coli.
(Select all that apply) A client is receiving ciprofloxacin IV for a severe infection caused by Pseudomonas aeruginosa.
Which of the following laboratory tests should the nurse monitor for adverse effects of this medication?
Explanation
Ciprofloxacin is an antibiotic that can cause various side effects, some of which are serious and may be permanent.
The nurse should monitor the following laboratory tests for adverse effects of this medication:
• Liver function tests: Ciprofloxacin can cause hepatotoxicity, which is damage to the liver cells.Liver function tests can detect abnormal levels of enzymes or bilirubin that indicate liver injury.
• Serum creatinine levels: Ciprofloxacin can cause nephrotoxicity, which is damage to the kidney cells.
Serum creatinine levels can measure how well the kidneys are filtering waste products from the blood.Elevated serum creatinine levels indicate impaired kidney function.
• Complete blood count: Ciprofloxacin can cause hematologic disorders, such as anemia, leukopenia, thrombocytopenia, or pancytopenia.
A complete blood count can evaluate the number and quality of red blood cells, white blood cells, and platelets in the blood.Abnormal blood counts can increase the risk of bleeding, infection, or fatigue.
Choice B is wrong because ciprofloxacin does not affect blood glucose levels directly.
However, ciprofloxacin can interact with some oral antidiabetic drugs and increase the risk of hypoglycemia or hyperglycemia.Therefore, the nurse should monitor the blood glucose levels of diabetic patients who are taking ciprofloxacin and other antidiabetic drugs.
Choice E is wrong because ciprofloxacin does not affect thyroid function tests directly.
However, ciprofloxacin can interact with some thyroid hormone replacement drugs and decrease their absorption or efficacy.Therefore, the nurse should monitor the thyroid function tests of patients who are taking ciprofloxacin and thyroid hormone replacement drugs.
A nurse is teaching a client who has a fungal infection about fluconazole.
Which of the following statements by the client indicates an understanding of the teaching?
Explanation
This is because alcohol can increase the risk of liver damage and other side effects from fluconazole.Fluconazole is an antifungal medicine that is used to treat infections caused by fungus, such as yeast infections.
Choice A is wrong because fluconazole can be taken with or without food.
Food does not affect the absorption of the medicine.
Choice C is wrong because fluconazole can reduce the effectiveness of hormonal contraceptives, such as birth control pills, patches, rings, or injections.Therefore, a barrier method of contraception, such as condoms or diaphragms, should be used in addition to the hormonal method while taking fluconazole and for at least 1 week after the last dose.
Choice D is wrong because a rash can be a sign of a serious allergic reaction to fluconazole.
If a rash develops, the medication should not be stopped without consulting a doctor.Other symptoms of an allergic reaction include hives, itching, swelling, difficulty breathing, or fever.
A client is diagnosed with influenza A and is prescribed oseltamivir.
Which of the following statements by the client indicates a need for further education?
Explanation
This statement indicates a need for further education because oseltamivir does not prevent the transmission of influenza virus to others.Oseltamivir is an antiviral drug that can shorten the duration of symptoms, reduce the risk of complications, and work best if started within 48 hours of symptom onset. However, it does not eliminate the virus from the body or provide immunity against future infections.Therefore, the client should still practice good hygiene and avoid contact with others who are at high risk of influenza complications.
Choice A is wrong because oseltamivir can shorten the duration of symptoms by about one day if taken within 48 hours of symptom onset.
Choice C is wrong because oseltamivir works best if started within 48 hours of symptom onset, as it inhibits the viral replication and reduces the viral load.
Choice D is wrong because oseltamivir may cause nausea and vomiting as side effects in some people, especially if taken without food.These side effects are usually mild and transient and can be minimized by taking the medication with food or milk.
A nurse is caring for a client who has meningitis caused by Streptococcus pneumoniae. The provider orders penicillin G IV for this client.
Before administering the medication, which of the following actions should the nurse take?
Explanation
This is because penicillin G is a beta-lactam antibiotic that can cause severe allergic reactions in some people, such as anaphylaxis, rash, or angioedema. Therefore, the nurse should always check for any history of allergies before administering penicillin G or any other beta-lactam antibiotic.
Choice A is wrong because checking the client’s temperature is not a priority action before giving penicillin G.Although fever is a common sign of meningitis, it does not affect the administration of penicillin
Choice B is wrong because assessing the client’s level of consciousness is not a priority action before giving penicillin G.Although altered mental status is a common sign of meningitis, it does not affect the administration of penicillin
Choice D is wrong because obtaining a blood sample for culture and sensitivity is not a priority action before giving penicillin G.Although culture and sensitivity tests are important to identify the causative organism and the appropriate antibiotic, they should not delay the initiation of empiric therapy for meningitis.Penicillin G is effective against Streptococcus pneumoniae, which is the most common cause of bacterial meningitis in adults.
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