Adverse effects of corticosteroids and immunosuppressants
Adverse effects of corticosteroids and immunosuppressants ( 5 Questions)
A nurse is monitoring a client who has asthma and is receiving fluticasone (Flovent), a corticosteroid, by inhalation. What are some of the outcomes that indicate the effectiveness of the therapy?
Decreased frequency and severity of asthma attacks, wheezing, coughing, and dyspnea . These are the main symptoms of asthma, a chronic respiratory condition that causes inflammation and narrowing of the airways, resulting in difficulty breathing. Fluticasone is a corticosteroid that works by reducing inflammation and mucus production in the airways. Fluticasone can prevent or reduce the occurrence and intensity of asthma attacks and improve the airflow and lung function in patients with asthma .
Increased appetite, weight gain, energy level, and quality of life are not outcomes that indicate the effectiveness of fluticasone therapy for asthma. These are outcomes that indicate the effectiveness of systemic corticosteroids such as prednisone or hydrocortisone, which are used to treat severe or life-threatening asthma exacerbations or other inflammatory conditions. Systemic corticosteroids have anti-inflammatory, immunosuppressive, and metabolic effects by binding to glucocorticoid receptors and modulating gene expression. Systemic corticosteroids can increase appetite, weight gain, energy level, and quality of life by reducing inflammation, pain, fatigue, and stress. However, systemic corticosteroids also have many adverse effects such as infection, osteoporosis, diabetes, hypertension, cataracts, glaucoma, mood changes, insomnia, acne. - Continue with the answer above. Systemic corticosteroids also have many adverse effects such as infection, osteoporosis, diabetes, hypertension, cataracts, glaucoma, mood changes, insomnia, acne, hirsutism, and adrenal suppression. Therefore, systemic corticosteroids should be used at the lowest effective dose and for the shortest possible duration to achieve the desired outcomes . Fluticasone is an inhaled corticosteroid that works locally in the lungs and has minimal systemic effects. Fluticasone does not have the same benefits or risks as systemic corticosteroids .
Normalized blood glucose, electrolytes, blood count, and liver function tests are not outcomes that indicate the effectiveness of fluticasone therapy for asthma. These are outcomes that indicate the prevention or reduction of adverse effects of systemic corticosteroids such as prednisone or hydrocortisone, which are used to treat severe or life-threatening asthma exacerbations or other inflammatory conditions. Systemic corticosteroids have anti-inflammatory, immunosuppressive, and metabolic effects by binding to glucocorticoid receptors and modulating gene expression. Systemic corticosteroids can affect blood glucose, electrolytes, blood count, and liver function tests by altering carbohydrate, protein, fat, water, and mineral metabolism. The nurse should monitor these parameters regularly and report any abnormal results or changes to the doctor. The nurse should also educate the client about the potential adverse effects of systemic corticosteroids and how to prevent or manage them. Fluticasone is an inhaled corticosteroid that works locally in the lungs and has minimal systemic effects. Fluticasone does not have the same effects or risks as systemic corticosteroids .
Reduced inflammation and mucus production in the airways is not an outcome that indicates the effectiveness of fluticasone therapy for asthma. This is a mechanism of action of fluticasone therapy for asthma. Fluticasone is a corticosteroid that works by reducing inflammation and mucus production in the airways. Fluticasone can prevent or reduce the occurrence and intensity of asthma attacks and improve the airflow and lung function in patients with asthma . However, this mechanism of action is not directly observable or measurable by the client or the nurse. The nurse should evaluate the outcomes that reflect the clinical improvement of asthma symptoms and signs such as decreased frequency and severity of asthma attacks, wheezing, coughing, and dyspnea; improved peak expiratory flow and forced expiratory volume in one second; and reduced need for rescue medication such as short-acting beta2 agonists.
Decreased frequency and severity of asthma attacks, wheezing, coughing, and dyspnea . These are the main symptoms of asthma, a chronic respiratory condition that causes inflammation and narrowing of the airways, resulting in difficulty breathing. Fluticasone is a corticosteroid that works by reducing inflammation and mucus production in the airways. Fluticasone can prevent or reduce the occurrence and intensity of asthma attacks and improve the airflow and lung function in patients with asthma .
The other options are incorrect because:
B. Increased appetite, weight gain, energy level, and quality of life are not outcomes that indicate the effectiveness of fluticasone therapy for asthma. These are outcomes that indicate the effectiveness of systemic corticosteroids such as prednisone or hydrocortisone, which are used to treat severe or life-threatening asthma exacerbations or other inflammatory conditions. Systemic corticosteroids have anti-inflammatory, immunosuppressive, and metabolic effects by binding to glucocorticoid receptors and modulating gene expression. Systemic corticosteroids can increase appetite, weight gain, energy level, and quality of life by reducing inflammation, pain, fatigue, and stress. However, systemic corticosteroids also have many adverse effects such as infection, osteoporosis, diabetes, hypertension, cataracts, glaucoma, mood changes, insomnia, acne. - Continue with the answer above. Systemic corticosteroids also have many adverse effects such as infection, osteoporosis, diabetes, hypertension, cataracts, glaucoma, mood changes, insomnia, acne, hirsutism, and adrenal suppression. Therefore, systemic corticosteroids should be used at the lowest effective dose and for the shortest possible duration to achieve the desired outcomes . Fluticasone is an inhaled corticosteroid that works locally in the lungs and has minimal systemic effects. Fluticasone does not have the same benefits or risks as systemic corticosteroids .
C. Normalized blood glucose, electrolytes, blood count, and liver function tests are not outcomes that indicate the effectiveness of fluticasone therapy for asthma. These are outcomes that indicate the prevention or reduction of adverse effects of systemic corticosteroids such as prednisone or hydrocortisone, which are used to treat severe or life-threatening asthma exacerbations or other inflammatory conditions. Systemic corticosteroids have anti-inflammatory, immunosuppressive, and metabolic effects by binding to glucocorticoid receptors and modulating gene expression. Systemic corticosteroids can affect blood glucose, electrolytes, blood count, and liver function tests by altering carbohydrate, protein, fat, water, and mineral metabolism. The nurse should monitor these parameters regularly and report any abnormal results or changes to the doctor. The nurse should also educate the client about the potential adverse effects of systemic corticosteroids and how to prevent or manage them. Fluticasone is an inhaled corticosteroid that works locally in the lungs and has minimal systemic effects. Fluticasone does not have the same effects or risks as systemic corticosteroids .
D. Reduced inflammation and mucus production in the airways is not an outcome that indicates the effectiveness of fluticasone therapy for asthma. This is a mechanism of action of fluticasone therapy for asthma. Fluticasone is a corticosteroid that works by reducing inflammation and mucus production in the airways. Fluticasone can prevent or reduce the occurrence and intensity of asthma attacks and improve the airflow and lung function in patients with asthma . However, this mechanism of action is not directly observable or measurable by the client or the nurse. The nurse should evaluate the outcomes that reflect the clinical improvement of asthma symptoms and signs such as decreased frequency and severity of asthma attacks, wheezing, coughing, and dyspnea; improved peak expiratory flow and forced expiratory volume in one second; and reduced need for rescue medication such as short-acting beta2 agonists.