Choice A rationale:

Postherpetic neuralgia is a potential complication of shingles. It occurs when nerve pain persists even after the rash has healed and can be a long-term and debilitating condition.

Choice B rationale:

Cranial nerve palsies can be a complication of shingles when the herpes zoster virus affects the cranial nerves, leading to neurological symptoms and complications.

Choice C rationale:

Bacterial superinfection is not a common complication of shingles. Shingles is caused by a viral infection, and while bacterial superinfection can occur if there is a secondary bacterial infection of the skin lesions, it is not a primary concern.

Choice D rationale:

Reye syndrome is not associated with shingles or its treatment. Reye syndrome is a rare but serious condition that primarily affects children recovering from viral infections, particularly those who have taken aspirin.

Choice E rationale:

Eye involvement is a potential complication of shingles, particularly if the herpes zoster virus affects the ophthalmic nerve, leading to eye pain, redness, and sometimes vision problems. Immediate medical attention is required in such cases to prevent complications that could lead to vision loss.