Drug-Food Interactions

Drug-Food Interactions ( 10 Questions)

A nurse is reviewing a client’s medication regimen and notes that the client is taking a medication that can interact with grapefruit juice. The nurse should instruct the client to avoid consuming grapefruit juice for how long before and after taking the medication? 



Correct Answer: D

Grapefruit juice can interact with certain medications by inhibiting the CYP3A4 enzyme, which is responsible for metabolizing many medications. To avoid this interaction, clients should avoid consuming grapefruit juice for at least 4 hours before and after taking the medication.

a. Avoiding grapefruit juice for only 15 minutes before and after taking the medication may not provide enough time to prevent an interaction. 

b. Avoiding grapefruit juice for only 30 minutes before and after taking the medication may not provide enough time to prevent an interaction. 

c. Avoiding grapefruit juice for only 1 hour before and after taking the medication may not provide enough time to prevent an interaction. 

d. Avoiding grapefruit juice for at least 4 hours before and after taking the medication provides enough time to prevent an interaction.




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