Hemolytic anemia
Hemolytic anemia ( 15 Questions)
A nurse is providing education to a group of clients with different types of hemolytic anemia.
Which types of hemolytic anemia are associated with abnormalities in the shape or structure of red blood cells? (Select all that apply)
Hereditary spherocytosis is a genetic disorder characterized by abnormal red blood cell membrane proteins, leading to a spherical shape instead of the normal biconcave disc shape.
G6PD deficiency is not associated with abnormalities in the shape or structure of red blood cells. Instead, it is characterized by red blood cell destruction due to a lack of the enzyme glucose-6-phosphate dehydrogenase.
Sickle cell anemia is caused by a mutation in the hemoglobin gene, leading to the formation of abnormal hemoglobin (hemoglobin S) that causes red blood cells to take on a sickle shape when oxygen levels are low.
Thalassemia intermedia is a form of thalassemia characterized by the production of abnormal hemoglobin molecules, leading to the destruction of red blood cells and potential changes in their structure.
Immune-mediated hemolytic anemia can result in the production of autoantibodies that attack red blood cells, leading to changes in their structure and function.
Hereditary spherocytosis.
C. Sickle cell anemia.
D. Thalassemia intermedia.
E. Immune-mediated hemolytic anemia.
Choice A rationale:
Hereditary spherocytosis is a genetic disorder characterized by abnormal red blood cell membrane proteins, leading to a spherical shape instead of the normal biconcave disc shape.
Choice C rationale:
Sickle cell anemia is caused by a mutation in the hemoglobin gene, leading to the formation of abnormal hemoglobin (hemoglobin S) that causes red blood cells to take on a sickle shape when oxygen levels are low.
Choice D rationale:
Thalassemia intermedia is a form of thalassemia characterized by the production of abnormal hemoglobin molecules, leading to the destruction of red blood cells and potential changes in their structure.
Choice E rationale:
Immune-mediated hemolytic anemia can result in the production of autoantibodies that attack red blood cells, leading to changes in their structure and function.
Choice B rationale:
G6PD deficiency is not associated with abnormalities in the shape or structure of red blood cells.
Instead, it is characterized by red blood cell destruction due to a lack of the enzyme glucose-6-phosphate dehydrogenase.