Immunity and Hypersensitivity

Immunity and Hypersensitivity ( 5 Questions)

A nurse is administering a blood transfusion to a client who has type AB blood. The nurse notices that the client develops fever, chills, back pain, and hemoglobinuria after receiving the blood. The nurse suspects that the client has developed what type of reaction?


Correct Answer: A

Choice B reason: An anaphylactic transfusion reaction is a type of transfusion reaction that occurs when the recipient has IgE antibodies against plasma proteins in the donor blood and causes a systemic allergic response. It manifests as urticaria, pruritus, bronchospasm, laryngeal edema, hypotension, or shock.

Choice C reason: A febrile nonhemolytic transfusion reaction is a type of transfusion reaction that occurs when the recipient has antibodies against leukocytes or platelets in the donor blood and causes a mild inflammatory response. It manifests as fever, chills, headache, or malaise.

Choice D reason: A transfusion-related acute lung injury is a type of transfusion reaction that occurs when the donor has antibodies against leukocytes in the recipient blood and causes pulmonary edema and respiratory distress. It manifests as dyspnea, hypoxia, hypotension, or fever.




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