Indications of corticosteroids and immunosuppressants
Indications of corticosteroids and immunosuppressants ( 4 Questions)
A nurse is teaching a client who has Crohn's disease and is prescribed azathioprine (Imuran), an antimetabolite. What should the nurse include in the teaching?
The drug may cause bone marrow suppression and increase the risk of infection and bleeding: Azathioprine can suppress the bone marrow, leading to decreased production of blood cells, including white blood cells, red blood cells, and platelets. This can increase the risk of infections, as well as bleeding tendencies.
The drug may cause nephrotoxicity and increase the risk of renal impairment and electrolyte imbalances: While azathioprine can have adverse effects on the kidneys in some cases, nephrotoxicity is not a commonly reported side effect. It is not a primary concern when using azathioprine in the treatment of Crohn's disease.
The drug may cause neurotoxicity and increase the risk of tremor, headache, and seizures: Neurotoxicity is not a commonly reported side effect of azathioprine. The potential for neurotoxicity is relatively low compared to other adverse effects associated with the medication.
The drug may cause hepatotoxicity and increase the risk of liver impairment and jaundice: Azathioprine has the potential to cause hepatotoxicity in some individuals, but it is not a commonly observed side effect. Liver impairment and jaundice are rare adverse effects associated with azathioprine use.
Azathioprine (Imuran) is an antimetabolite medication that is commonly used in the treatment of Crohn's disease. It works by suppressing the immune system and reducing inflammation. When teaching a client about azathioprine, the nurse should include important information about potential side effects and adverse reactions.
A. The drug may cause bone marrow suppression and increase the risk of infection and bleeding: Azathioprine can suppress the bone marrow, leading to decreased production of blood cells, including white blood cells, red blood cells, and platelets. This can increase the risk of infections, as well as bleeding tendencies.
B. The drug may cause nephrotoxicity and increase the risk of renal impairment and electrolyte imbalances: While azathioprine can have adverse effects on the kidneys in some cases, nephrotoxicity is not a commonly reported side effect. It is not a primary concern when using azathioprine in the treatment of Crohn's disease.
C. The drug may cause neurotoxicity and increase the risk of tremor, headache, and seizures: Neurotoxicity is not a commonly reported side effect of azathioprine. The potential for neurotoxicity is relatively low compared to other adverse effects associated with the medication.
D. The drug may cause hepatotoxicity and increase the risk of liver impairment and jaundice: Azathioprine has the potential to cause hepatotoxicity in some individuals, but it is not a commonly observed side effect. Liver impairment and jaundice are rare adverse effects associated with azathioprine use.