Major depressive disorder (MDD)

Major depressive disorder (MDD) ( 20 Questions)

A nurse is discussing the theories that explain the biological basis of Major Depressive Disorder (MDD) with a group of nursing students. Which theory suggests that depression is caused by an imbalance of neurotransmitters in the brain that regulate mood, motivation, reward, cognition, and stress response?


Correct Answer: C

Choice A rationale:

Genetic theory suggests that a person's genetic makeup can predispose them to develop depression, but it does not specifically address the role of neurotransmitters in depression. While genetics can contribute to the risk of major depressive disorder (MDD), this choice doesn't focus on the neurotransmitter imbalances.

Choice B rationale:

Neuroendocrine theory pertains to the role of hormones in depression, particularly abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis. While hormones play a role in mood regulation, this theory does not primarily revolve around neurotransmitter imbalances.

Choice C rationale:

Neurotransmitter theory proposes that an imbalance of neurotransmitters, such as serotonin, norepinephrine, and dopamine, contributes to the development of major depressive disorder. This theory aligns with the idea that these neurotransmitters are responsible for regulating mood, motivation, reward, cognition, and stress response.

Choice D rationale:

Environmental theory suggests that external factors, such as life events and stressors, contribute to the development of depression. While environment can indeed influence depression, it does not specifically address the neurotransmitter imbalances that are central to this question.




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