Opioid Analgesics

Opioid Analgesics ( 5 Questions)

A nurse is reviewing the medication history of a client who is prescribed buprenorphine for chronic pain.
The nurse should identify that which medication can interact with buprenorphine and increase the risk of serotonin syndrome?



Correct Answer: A

Fluoxetine can interact with buprenorphine and increase the risk of serotonin syndrome. Serotonin syndrome is a serious drug reaction that occurs when there is too much serotonin in the body. It can cause symptoms such as agitation, confusion, muscle rigidity, fever, seizures and coma.

Choice B is wrong because metformin is not known to have any serotonergic effects or interact with buprenorphine.

Choice C is wrong because omeprazole is not known to have any serotonergic effects or interact with buprenorphine.

Choice D is wrong because lisinopril is not known to have any serotonergic effects or interact with buprenorphine.




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