Summary

Summary ( 4 Questions)

A nurse is caring for a client who has a malignant tumor in the colon. The nurse understands that neoplasia is the abnormal and uncontrolled growth of cells that can invade and destroy normal tissues. Which of the following factors can contribute to neoplasia? (Select all that apply.)


Correct Answer: ["A","B","C","D"]

Choice A reason:

Genetic mutations are a factor that can contribute to neoplasia. Genetic mutations are changes in the DNA sequence of a cell that can affect its normal function and regulation. Some genetic mutations are inherited, while others are acquired due to environmental factors, such as radiation, chemicals, or smoking. Genetic mutations can cause oncogenes to be activated or tumor suppressor genes to be inactivated, which can result in uncontrolled cell proliferation and resistance to apoptosis.

Choice B reason:

Hormonal imbalances are a factor that can contribute to neoplasia. Hormonal imbalances are abnormal levels of hormones in the body that can affect the growth and differentiation of cells. Some hormones, such as estrogen and progesterone, can stimulate the growth of certain types of cells, such as breast and endometrial cells. Hormonal imbalances can increase the risk of developing hormone-dependent cancers, such as breast cancer or endometrial cancer.

Choice C reason:

Chronic inflammation is a factor that can contribute to neoplasia. Chronic inflammation is a prolonged and persistent inflammatory response that can damage normal tissues and cause tissue repair and regeneration. Chronic inflammation can increase the production of reactive oxygen species (ROS) and cytokines, which can induce DNA damage and genetic mutations. Chronic inflammation can also stimulate angiogenesis and invasion of inflammatory cells, which can promote tumor growth and metastasis.

Choice D reason:

Viral infections are a factor that can contribute to neoplasia. Viral infections are invasions of viruses into host cells that can cause disease or harm. Some viruses, such as human papillomavirus (HPV), hepatitis B virus (HBV), hepatitis C virus (HCV), Epstein-Barr virus (EBV), and human immunodeficiency virus (HIV), can cause neoplasia by integrating their DNA into the host cell's genome and altering its normal function and regulation. Viral infections can also impair the immune system's ability to recognize and eliminate abnormal cells.

Choice E reason:

Nutritional deficiencies are not a factor that can contribute to neoplasia. Nutritional deficiencies are inadequate intake or absorption of essential nutrients that can affect the health and function of various organs and systems. Nutritional deficiencies can increase the risk of developing infections or chronic diseases, but they do not directly cause neoplasia. However, some nutrients, such as antioxidants, vitamins, minerals, and fiber, may have protective effects against neoplasia by preventing oxidative stress, enhancing immune function, or modulating hormonal levels.




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