Thrombocytopenia
Thrombocytopenia ( 15 Questions)
What is the likely cause of thrombocytopenia in this patient?
"Increased platelet production due to chemotherapy." Rationale: This statement is not accurate. Chemotherapy often suppresses bone marrow function, leading to a decrease in platelet production, not an increase. Thrombocytopenia is a common side effect of chemotherapy due to reduced platelet production.
"Immune-mediated platelet destruction caused by chemotherapy." Rationale: This statement is correct. Thrombocytopenia in patients undergoing chemotherapy is often due to immune-mediated platelet destruction. Chemotherapy can trigger an autoimmune response, leading to the destruction of platelets by the immune system.
"Thrombocytopenia in this case is unrelated to chemotherapy." Rationale: This statement is unlikely to be true. Thrombocytopenia occurring in a patient following chemotherapy is often directly related to the treatment. While other factors may contribute, chemotherapy is a known cause of decreased platelet counts.
"Thrombocytopenia results from the inhibition of platelet aggregation by chemotherapy." Rationale: This statement is not accurate. Chemotherapy primarily affects platelet production and can lead to a decrease in platelet count. It does not typically inhibit platelet aggregation.
Choice A rationale:
"Increased platelet production due to chemotherapy." Rationale: This statement is not accurate.
Chemotherapy often suppresses bone marrow function, leading to a decrease in platelet production, not an increase.
Thrombocytopenia is a common side effect of chemotherapy due to reduced platelet production.
Choice B rationale:
"Immune-mediated platelet destruction caused by chemotherapy." Rationale: This statement is correct.
Thrombocytopenia in patients undergoing chemotherapy is often due to immune-mediated platelet destruction.
Chemotherapy can trigger an autoimmune response, leading to the destruction of platelets by the immune system.
Choice C rationale:
"Thrombocytopenia in this case is unrelated to chemotherapy." Rationale: This statement is unlikely to be true.
Thrombocytopenia occurring in a patient following chemotherapy is often directly related to the treatment.
While other factors may contribute, chemotherapy is a known cause of decreased platelet counts.
Choice D rationale:
"Thrombocytopenia results from the inhibition of platelet aggregation by chemotherapy." Rationale: This statement is not accurate.
Chemotherapy primarily affects platelet production and can lead to a decrease in platelet count.
It does not typically inhibit platelet aggregation.