Types of Drug Interactions
Types of Drug Interactions ( 14 Questions)
A nurse is reviewing a client’s medication regimen and notes that the client is taking two medications that are both highly protein-bound. The nurse should recognize that this can result in which of the following?
An increased free fraction can result in higher plasma concentrations and an increased risk of adverse effects.
Competition for binding sites can decrease the effectiveness of one or both medications by decreasing their plasma concentrations.
Altered distribution can occur because changes in protein binding can affect how much medication is distributed to tissues. d. All of these effects can occur when two highly protein-bound medications are taken together.
When two highly protein-bound medications are taken together, they can compete for binding sites on plasma proteins. This can result in an increased free fraction of one or both medications, leading to an increased risk of adverse effects, decreased effectiveness, and altered distribution.
When two highly protein-bound medications are taken together, they can compete for binding sites on plasma proteins. This can result in an increased free fraction of one or both medications, leading to an increased risk of adverse effects, decreased effectiveness, and altered distribution.
a. An increased free fraction can result in higher plasma concentrations and an increased risk of adverse effects.
b. Competition for binding sites can decrease the effectiveness of one or both medications by decreasing their plasma concentrations.
c. Altered distribution can occur because changes in protein binding can affect how much medication is distributed to tissues. d. All of these effects can occur when two highly protein-bound medications are taken together.