Commonly prescribed antimicrobial agents
Commonly prescribed antimicrobial agents ( 5 Questions)
A nurse is reviewing the medication history of a client who has a bacterial gastrointestinal infection and a prescription for metronidazole (Flagyl).
The nurse should identify that which of the following medications can interact with metronidazole?
Warfarin (Coumadin) can interact with metronidazole (Flagyl) and increase the risk of bleeding. This is because metronidazole may inhibit the enzyme that metabolizes warfarin, leading to higher warfarin levels and enhanced anticoagulant effect. If a patient is taking warfarin and metronidazole, they may need a dose adjustment and frequent monitoring of their INR. They should also watch for any signs of bleeding or bruising and report them to their doctor.
Choice B is wrong because levothyroxine (Synthroid) does not have a significant interaction with metronidazole.
Choice C is wrong because lisinopril (Prinivil) does not have a significant interaction with metronidazole.
Choice D is wrong because omeprazole (Prilosec) does not have a significant interaction with metronidazole.
Warfarin (Coumadin) can interact with metronidazole (Flagyl) and increase the risk of bleeding. This is because metronidazole may inhibit the enzyme that metabolizes warfarin, leading to higher warfarin levels and enhanced anticoagulant effect. If a patient is taking warfarin and metronidazole, they may need a dose adjustment and frequent monitoring of their INR. They should also watch for any signs of bleeding or bruising and report them to their doctor.
Choice B is wrong because levothyroxine (Synthroid) does not have a significant interaction with metronidazole.
Choice C is wrong because lisinopril (Prinivil) does not have a significant interaction with metronidazole.
Choice D is wrong because omeprazole (Prilosec) does not have a significant interaction with metronidazole.