Factors Affecting Drug Interactions

Factors Affecting Drug Interactions ( 10 Questions)

A patient has been prescribed two drugs with one being an antagonist and another being a partial agonist at the same receptor. What will be their combined effect? 



Correct Answer: D

An antagonist will increase a partial agonist’s action by competing for binding at the same receptor and decreasing the basal activity.

a. Increasing the antagonist’s action will not occur as an antagonist will increase a partial agonist’s action by competing for binding at the same receptor and decreasing the basal activity. 

b. Decreasing the antagonist’s action will not occur as an antagonist will increase a partial agonist’s action by competing for binding at the same receptor and decreasing the basal activity. 

c. No change will not occur as an antagonist will increase a partial agonist’s action by competing for binding at the same receptor and decreasing the basal activity. 

d. Increasing partial agonist’s action will occur due to competition for binding at the same receptor by an antagonist and decreasing the basal activity.




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