Further Questions on this Topic
Further Questions on this Topic ( 18 Questions)
Type I hypersensitivity is not involved in Graves' disease, as it does not involve IgE antibodies or mast cells.
Type II hypersensitivity is involved in Graves' disease, as it involves IgG antibodies that bind to the thyroid-stimulating hormone (TSH) receptors on the thyroid gland and stimulate the production of thyroid hormones. This leads to hyperthyroidism and manifestations such as goiter, exophthalmos, tachycardia, weight loss, or tremors.
Type III hypersensitivity is not involved in Graves' disease, as it does not involve immune complexes or complement activation.
Type IV hypersensitivity is not involved in Graves' disease, as it does not involve cytotoxic T cells or helper T cells.
Type V hypersensitivity is also involved in Graves' disease, as it involves the stimulation of target cells by antibodies that act as agonists for cell surface receptors. This leads to an increased function of the target organ or tissue.
Choice A reason:
Type I hypersensitivity is not involved in Graves' disease, as it does not involve IgE antibodies or mast cells.
Choice B reason:
Type II hypersensitivity is involved in Graves' disease, as it involves IgG antibodies that bind to the thyroid-stimulating hormone (TSH) receptors on the thyroid gland and stimulate the production of thyroid hormones. This leads to hyperthyroidism and manifestations such as goiter, exophthalmos, tachycardia, weight loss, or tremors.
Choice C reason:
Type III hypersensitivity is not involved in Graves' disease, as it does not involve immune complexes or complement activation.
Choice D reason:
Type IV hypersensitivity is not involved in Graves' disease, as it does not involve cytotoxic T cells or helper T cells.
Choice E reason:
Type V hypersensitivity is also involved in Graves' disease, as it involves the stimulation of target cells by antibodies that act as agonists for cell surface receptors. This leads to an increased function of the target organ or tissue.