Mixed Agonists/Antagonists
Mixed Agonists/Antagonists ( 5 Questions)
A nurse is administering dezocine (Dalgan) to a client who has moderate pain due to kidney stones.
The nurse should explain to the client that this medication works by which of the following mechanisms?
Dezocine does not block the transmission of pain impulses in the spinal cord.
That is the mechanism of action of local anesthetics.
Dezocine is a partial agonist of the μ-opioid receptor and an antagonist of the κ-opioid receptor. It binds with stereospecific receptors at many sites within the central nervous system (CNS) to alter processes affecting both the perception of pain and the emotional response to pain.
Dezocine does not inhibit prostaglandin synthesis in peripheral tissues.
That is the mechanism of action of nonsteroidal anti-inflammatory drugs (NSAIDs).
Dezocine does not stimulate endorphin release in the central nervous system.
Dezocine is a partial agonist of the μ-opioid receptor and an antagonist of the κ-opioid receptor. It binds with stereospecific receptors at many sites within the central nervous system (CNS) to alter processes affecting both the perception of pain and the emotional response to pain.
Choice A is wrong because dezocine does not block the transmission of pain impulses in the spinal cord.
That is the mechanism of action of local anesthetics.
Choice C is wrong because dezocine does not inhibit prostaglandin synthesis in peripheral tissues.
That is the mechanism of action of nonsteroidal anti-inflammatory drugs (NSAIDs).
Choice D is wrong because dezocine does not stimulate endorphin release in the central nervous system.