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A nurse is caring for a client who has bipolar disorder and is prescribed lamotrigine (Lamictal). Which of the following instructions should be included in the teaching? (Select all that apply.)



Correct Answer: A

Lamotrigine can cause a serious and potentially life-threatening skin reaction called Stevens-Johnson syndrome, which causes flu-like symptoms, followed by a red or purple rash that spreads and forms blisters. This is more likely to happen in the first 8 weeks of starting lamotrigine, or when the dose is increased too quickly. Therefore, the nurse should instruct the client to report any signs of rash immediately and stop taking the medication until further evaluation.

Choice B is wrong because lamotrigine can be taken with or without food. Taking it with food does not affect its absorption or effectiveness.

Choice C is wrong because lamotrigine does not affect hormonal contraceptives, and vice versa. However, the nurse should advise the client to inform their doctor if they are pregnant or planning to become pregnant, as lamotrigine may have some risks for the fetus.

Choice D is wrong because lamotrigine may take several weeks or months to show therapeutic effects, depending on the condition being treated. The nurse should encourage the client to be patient and adhere to the prescribed regimen.

Choice E is wrong because lamotrigine does not interact with grapefruit juice. However, the nurse should advise the client to avoid alcohol, as it may increase the risk of side effects such as drowsiness, dizziness, and seizures.




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