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A nurse is reviewing the laboratory results of a client who uses probiotics as biologically based therapies for his irritable bowel syndrome (IBS). The nurse should expect that probiotics may have which of the following effects on the client's laboratory results?
Decrease in fecal pH and increase in fecal short-chain fatty acids is a possible effect of probiotics on the client's laboratory results. This is because probiotics, especially those containing LAB, can ferment dietary fibers and produce short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate. SCFAs can lower the fecal pH and have beneficial effects on the intestinal microbiota, mucosal barrier, immune system, and metabolism¹².
Increase in fecal pH and decrease in fecal short-chain fatty acids is not a likely effect of probiotics on the client's laboratory results. This is because probiotics, especially those containing LAB, tend to have the opposite effect, as explained above.
Decrease in serum cholesterol and triglyceride levels is not a consistent or conclusive effect of probiotics on the client's laboratory results. This is because the evidence for the lipid-lowering effects of probiotics is mixed and depends on various factors, such as the type, dose, duration, and formulation of probiotics, as well as the baseline lipid levels, diet, and lifestyle of the client³⁴.
Increase in serum cholesterol and triglyceride levels is not a common or expected effect of probiotics on the client's laboratory results. This is because most probiotics do not have adverse effects on lipid metabolism and may even have beneficial effects in some cases, as mentioned above..
Choice A reason: Decrease in fecal pH and increase in fecal short-chain fatty acids is a possible effect of probiotics on the client's laboratory results. This is because probiotics, especially those containing LAB, can ferment dietary fibers and produce short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate. SCFAs can lower the fecal pH and have beneficial effects on the intestinal microbiota, mucosal barrier, immune system, and metabolism¹².
Choice B reason: Increase in fecal pH and decrease in fecal short-chain fatty acids is not a likely effect of probiotics on the client's laboratory results. This is because probiotics, especially those containing LAB, tend to have the opposite effect, as explained above.
Choice C reason: Decrease in serum cholesterol and triglyceride levels is not a consistent or conclusive effect of probiotics on the client's laboratory results. This is because the evidence for the lipid-lowering effects of probiotics is mixed and depends on various factors, such as the type, dose, duration, and formulation of probiotics, as well as the baseline lipid levels, diet, and lifestyle of the client³⁴.
Choice D reason: Increase in serum cholesterol and triglyceride levels is not a common or expected effect of probiotics on the client's laboratory results. This is because most probiotics do not have adverse effects on lipid metabolism and may even have beneficial effects in some cases, as mentioned above..