Choice A rationale:

Hemoglobin electrophoresis is not primarily used to measure the number and size of red blood cells.

It focuses on the types of hemoglobin present in the blood, not their quantity or size.

Choice B rationale:

The primary purpose of hemoglobin electrophoresis in the diagnostic workup for sickle cell disease (SCD) is to identify the presence and amount of abnormal hemoglobins.

This test helps diagnose and differentiate various types of hemoglobinopathies, including SCD.

Abnormal hemoglobins like hemoglobin S (HbS) are characteristic of SCD.

Choice C rationale:

Hemoglobin electrophoresis does not expose a blood sample to a deoxygenating agent.

Instead, it separates hemoglobin molecules based on their electrical charge, which is useful for identifying abnormal hemoglobins associated with SCD.

Choice D rationale:

Hemoglobin electrophoresis does not analyze the DNA of a blood sample.

It primarily focuses on the characterization of hemoglobin types and their proportions within the blood.