Types of Drug Interactions
Types of Drug Interactions ( 14 Questions)
A nurse is reviewing a client’s medication regimen and notes that the client is taking a medication that is known to be a substrate for CYP450 enzymes. The nurse should recognize that this can result in which of the following?
An increased risk of adverse effects can occur because changes in CYP450 enzyme activity can affect how quickly the medication is metabolized and eliminated from the body.
Decreased effectiveness can occur because changes in CYP450 enzyme activity can affect how much active drug is available to produce a therapeutic effect.
Altered metabolism can occur because changes in CYP450 enzyme activity can affect how the medication is metabolized and eliminated from the body.
CYP450 enzymes are responsible for metabolizing many medications. If a client is taking a medication that is a substrate for these enzymes, it can result in an increased risk of adverse effects, decreased effectiveness, and altered metabolism.
CYP450 enzymes are responsible for metabolizing many medications. If a client is taking a medication that is a substrate for these enzymes, it can result in an increased risk of adverse effects, decreased effectiveness, and altered metabolism.
a. An increased risk of adverse effects can occur because changes in CYP450 enzyme activity can affect how quickly the medication is metabolized and eliminated from the body.
b. Decreased effectiveness can occur because changes in CYP450 enzyme activity can affect how much active drug is available to produce a therapeutic effect.
c. Altered metabolism can occur because changes in CYP450 enzyme activity can affect how the medication is metabolized and eliminated from the body.
d. All of these effects can occur when a client is taking a medication that is a substrate for CYP450 enzymes.