Antimicrobial classifications
Antimicrobial classifications ( 11 Questions)
A nurse is caring for a client who has a viral infection and is taking an antiviral medication that inhibits the integrase enzyme that is essential for viral DNA integration into host cell genome. Which of the following antiviral groups does this medication belong to?
Choice A is wrong because nucleotide reverse transcriptase inhibitors (NRTIs) are a class of antiviral drugs that block the action of reverse transcriptase, a viral enzyme that converts the viral RNA into DNA.
Choice B is wrong because non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a class of antiviral drugs that also block the action of reverse transcriptase, but in a different way than NRTIs. They bind to a different site on the enzyme and cause it to change shape.
Integrase strand transfer inhibitors (INSTIs) are a class of antiviral drugs that block the action of integrase, a viral enzyme that inserts the viral genome into the DNA of the host cell. This prevents the virus from replicating and infecting new cells.
Choice D is wrong because protease inhibitors (PIs) are a class of antiviral drugs that block the action of protease, a viral enzyme that cleaves the viral polyprotein into functional units. This prevents the virus from assembling and maturing.
Integrase strand transfer inhibitors (INSTIs) are a class of antiviral drugs that block the action of integrase, a viral enzyme that inserts the viral genome into the DNA of the host cell. This prevents the virus from replicating and infecting new cells.
Choice A is wrong because nucleotide reverse transcriptase inhibitors (NRTIs) are a class of antiviral drugs that block the action of reverse transcriptase, a viral enzyme that converts the viral RNA into DNA.
Choice B is wrong because non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a class of antiviral drugs that also block the action of reverse transcriptase, but in a different way than NRTIs. They bind to a different site on the enzyme and cause it to change shape.
Choice D is wrong because protease inhibitors (PIs) are a class of antiviral drugs that block the action of protease, a viral enzyme that cleaves the viral polyprotein into functional units. This prevents the virus from assembling and maturing.