Hesi Pharmacology exam 2
Hesi Pharmacology exam 2 ( 36 Questions)
A client is receiving intravenous (IV) vancomycin and the nurse plans to draw blood for a peak and trough to determine the serum level of the drug. Which collection times provide the best determination of these levels?
Peak and trough levels are essential in monitoring the therapeutic drug levels of certain medications, including vancomycin. The timing of blood collection is crucial to obtain accurate readings. Peak level: The peak level is drawn approximately 30 minutes after the completion of the vancomycin infusion. This is when the drug concentration in the bloodstream is at its highest, allowing the healthcare provider to assess if the dosage is achieving the desired therapeutic effect. Trough level: The trough level is drawn just before the next dose of vancomycin is administered, typically within 30 minutes before the scheduled time. This is when the drug concentration in the bloodstream is at its lowest, ensuring that the levels do not fall below the therapeutic range between doses. By drawing blood samples two hours after the completion of the IV dose and two hours before the next administration, the nurse can accurately determine both the peak and trough levels, providing crucial information for evaluating the client's response to the medication and adjusting the dosage as needed.
While this option may provide some information, it does not allow for an accurate determination of both the peak and trough levels. The peak level should be drawn closer to the completion of the infusion (around 30 minutes), and the trough level should be drawn just before the next dose (within 30 minutes).
This timing does not allow for accurate peak and trough level determination. The peak level should be drawn closer to the completion of the infusion (around 30 minutes), and the trough level should be drawn just before the next dose (within 30 minutes).
Immediately after completion of the IV dose and 30 minutes before the next administration of the medication: Drawing the peak level immediately after the completion of the IV dose may not accurately reflect the highest drug concentration in the bloodstream. The peak level should be drawn around 30 minutes after completion of the infusion for accurate determination. Additionally, the trough level should be drawn within 30 minutes before the next dose, not necessarily 30 minutes before the next administration.
Choice A rationale: Peak and trough levels are essential in monitoring the therapeutic drug levels of certain medications, including vancomycin. The timing of blood collection is crucial to obtain accurate readings. Peak level: The peak level is drawn approximately 30 minutes after the completion of the vancomycin infusion. This is when the drug concentration in the bloodstream is at its highest, allowing the healthcare provider to assess if the dosage is achieving the desired therapeutic effect. Trough level: The trough level is drawn just before the next dose of vancomycin is administered, typically within 30 minutes before the scheduled time. This is when the drug concentration in the bloodstream is at its lowest, ensuring that the levels do not fall below the therapeutic range between doses. By drawing blood samples two hours after the completion of the IV dose and two hours before the next administration, the nurse can accurately determine both the peak and trough levels, providing crucial information for evaluating the client's response to the medication and adjusting the dosage as needed.
Choice B rationale: While this option may provide some information, it does not allow for an accurate determination of both the peak and trough levels. The peak level should be drawn closer to the completion of the infusion (around 30 minutes), and the trough level should be drawn just before the next dose (within 30 minutes).
Choice C rationale: This timing does not allow for accurate peak and trough level determination. The peak level should be drawn closer to the completion of the infusion (around 30 minutes), and the trough level should be drawn just before the next dose (within 30 minutes).
Choice D rationale: Immediately after completion of the IV dose and 30 minutes before the next administration of the medication: Drawing the peak level immediately after the completion of the IV dose may not accurately reflect the highest drug concentration in the bloodstream. The peak level should be drawn around 30 minutes after completion of the infusion for accurate determination. Additionally, the trough level should be drawn within 30 minutes before the next dose, not necessarily 30 minutes before the next administration.