Pharmacological and Non-Pharmacological Interventions for Pain Relief in Children

Pharmacological and Non-Pharmacological Interventions for Pain Relief in Children ( 28 Questions)

A client's child is prescribed ibuprofen for mild to moderate pain and inflammation.
The client asks the nurse, ".”..
Which statement accurately describes the mechanism of action of ibuprofen in reducing pain, inflammation, and fever in pediatric patients?


Correct Answer: A

Choice A rationale:

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the synthesis of prostaglandins.

Prostaglandins are chemicals in the body that promote inflammation, pain, and fever.

By blocking their production, ibuprofen reduces these symptoms.

Specifically, it inhibits the activity of the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), which are involved in prostaglandin synthesis.

This mechanism of action makes ibuprofen effective in alleviating pain, reducing inflammation, and lowering fever in pediatric patients.

Choice B rationale:

This choice is incorrect.

Ibuprofen does not bind to opioid receptors or alter pain perception.

It has a different mechanism of action as an NSAID.

Choice C rationale:

Ibuprofen does not enhance neurotransmitter activity to increase the pain threshold.

Its primary action is on prostaglandin synthesis and inflammation, not neurotransmitters.

Choice D rationale:

Ibuprofen does not block calcium channels or reduce pain signal transmission in the manner described.

Its primary mechanism is the inhibition of prostaglandin synthesis.




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