"Gout is caused by a bacterial infection in the joints." This statement is not accurate.

Gout is not caused by a bacterial infection.

Gout results from the accumulation of uric acid crystals in the joints, leading to inflammation and pain.

Choice C rationale:

"Gout occurs when there is too much calcium buildup in the joint spaces." This statement is incorrect.

Gout is primarily associated with the buildup of uric acid crystals, not calcium.

Calcium deposits in joints are more commonly seen in conditions like calcium pyrophosphate deposition disease (CPPD) or pseudogout.

Choice D rationale:

"Gout is primarily due to an autoimmune response targeting joint tissues." This statement is inaccurate.

Gout is not primarily an autoimmune disorder.

It is a metabolic disorder characterized by the deposition of uric acid crystals in joints, which triggers an inflammatory response.

Autoimmune disorders involve the immune system mistakenly attacking the body's own tissues, which is not the case in gout.