Pharmacokinetics

Pharmacokinetics ( 10 Questions)

A nurse is preparing to administer a prodrug that requires activation by hepatic enzymes.What should be considered when administering this drug?



Correct Answer: A

A prodrug is an inactive compound that requires conversion into its active form by metabolic processes such as hepatic enzyme activation.Giving a prodrug with an enzyme inducer can increase the activity of the hepatic enzymes responsible for converting the prodrug into its active form, potentially increasing its efficacy.

a.Giving the drug with food may affect its absorption but does not directly affect its activation by hepatic enzymes.

b.Giving the drug with food may affect its absorption but does not directly affect its activation by hepatic enzymes.

c.Giving the drug with an enzyme inducer, not an enzyme inhibitor, can increase its efficacy by increasing hepatic enzyme activity.




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