Tuberculosis

Tuberculosis ( 23 Questions)

Select the correct statements regarding drug-resistant TB. Select all that apply:


Correct Answer: ["A","B","C","E"]

Choice A rationale:

MDR-TB stands for multidrug-resistant tuberculosis, and it is resistant to at least two of the most potent first-line anti-TB drugs, isoniazid (INH), and rifampicin (RIF) This resistance makes the treatment of MDR-TB more challenging and requires the use of second-line drugs.

Choice B rationale:

XDR-TB stands for extensively drug-resistant tuberculosis, and it is resistant to all first-line anti-TB drugs (INH and RIF) and at least one of the second-line injectable drugs (e.g., amikacin, kanamycin, or capreomycin) XDR-TB is even more challenging to treat than MDR-TB and requires the use of third-line drugs.

Choice C rationale:

RR-TB refers to rifampicin-resistant tuberculosis. It is resistant to rifampicin alone or in combination with other drugs but still susceptible to isoniazid. Rifampicin resistance is a critical indicator for diagnosing MDR-TB.

Choice D rationale:

This statement is incorrect. Drug-resistant TB is not more common in infants and children. It can affect individuals of any age, especially those who have received inadequate or inappropriate treatment for TB, leading to the development of drug resistance.

Choice E rationale:

This statement is correct. Drug-resistant TB requires more prolonged treatment compared to drug-sensitive TB. Treatment for drug-resistant TB can take months to years and often involves a combination of second and third-line drugs, which may have more side effects and require careful monitoring.

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